منابع مشابه
Cancer therapy with phytochemicals: evidence from clinical studies
Cancer is still one of the major causes of mortality in both developing and developed countries. At this time, in spite of intensive interventions, a large number of patients have poor prognosis. Therefore, the effort for finding new anticancer agents with better efficacy and lesser side effects has continued. According to the traditional recommendations and experimental studies, numerous medic...
متن کاملStructural studies on the degradation products of vincristine dihydrogen sulfate.
Vincristine was incubated at 37 degrees C for 72 h in 0.2 M glycine buffer (pH 7.4 or 8.8) containing 1% bovine serum albumin. The reaction mixture was extracted with CH2Cl2. High-performance liquid chromatography analysis (muBondapak C18 reverse-phase 10-micron steel column; solvent, 50% MeOH in 10 mM KH2PO4, pH 4.5; flow rate, 1.2 ml/min) of the CH2Cl2 extract gave 6 peaks, A, B, C, D, E, and...
متن کاملDFT studies of nano anticancer on vinblastine and vincristine molecules
1 M.Sc student, Science and Research Branch, Islamic Azad University, Tehran, Iran. 2 Department of Chemistry, Yazd Branch, Islamic Azad University, Yazd, Iran 3 Ph.D Student, Yazd Branch, Islamic Azad University, Yazd, Iran 4 Ph.D Student, Science and Research Branch, Islamic Azad University, Tehran, Iran. 5 Department of Chemistry, Science and Research Branch, Islamic Azad University, Tehran,...
متن کاملComa associated with vincristine therapy.
Three cases of coma after vincristine therapy are described. One patient had hyponatraemia and other features of inappropriate secretion of antidiuretic hormone. The effects were temporary, and full recovery occurred in all three patients.
متن کاملExperience with vincristine--associated neurotoxicity.
OBJECTIVES To evaluate the frequency and severity of occurrence of vincristine-associated neurotoxicity. DESIGN A retrospective case series study. SETTING Hurlingham Oncology Clinic, Nairobi. SUBJECTS Thirty-eight patients treated for various neoplasms with vincristine containing chemotherapeutic regimens. MAIN OUTCOME MEASURES The frequency and degree of neurotoxicity when vincristine ...
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ژورنال
عنوان ژورنال: Blood
سال: 1963
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v21.5.640.640